Safety baseline
Prioritize evidence quality, adverse effects, and medical contraindications.
THE BIOHACKING REFERENCE
The purpose, safety principles, and ongoing development of this independent educational reference.
This site is designed as a living encyclopedia for human biohacking topics, from baseline biology and nutrition to advanced areas like closed-loop digital therapeutics, gene-level technologies, and neuromodulation.
The Journal of Biohacking reports on doses; it does not prescribe them. Where we describe how a peptide, supplement, medicine or gene therapy has been used, we are reporting two things only: what published research has tested, and what prominent members of the biohacking community say they use. Each figure is attributed to its source, because both science and regulation move quickly.
These reports are journalism, not counsel. Nothing we publish is a recommendation of the Journal of Biohacking, and nothing is a proposal for how any molecule, product or gene therapy should be used, by you or by anyone. A dose that appears in a trial was chosen for a particular population under medical supervision; a dose that appears in a community account reflects one person’s choices. Neither is a guide to yours.
Many of the substances we cover are not approved by the U.S. Food and Drug Administration, and some carry serious, poorly understood risks. We do not offer individual advice, answer personal dosing questions or sell any product. Decisions about your health belong with you and a licensed clinician who knows your history.
We accept no payment that touches our dosing coverage, and pages that discuss dosing carry no advertising or affiliate links.
This build prioritizes a reproducible knowledge architecture so we can keep expanding to full A-Z completeness while preserving evidence quality, safety context, and clear practical boundaries.
Prioritize evidence quality, adverse effects, and medical contraindications.
Protect autonomy, avoid coercive optimization culture, and respect informed consent in shared environments (workplaces, teams, schools).
Secure personal biomarkers, use local-first storage where possible, and minimize unnecessary sharing of health data.
Track device approvals, supplement classifications, and regional practice restrictions.